The program only works on Windows, but it can create ISO for software installation that works on Mac, Linux, and other operating systems. Rufus is … So basically, what Rufus does is it does the formatting to create bootable USB flash drives so we can use it to install the Windows 10 ISO instead of using the traditional CD-ROM or floppy disk drives. Rufus is an open-source program that can create a UEFI bootable USB by using an existing ISO file.